产品货号：
Z36790
中文名称：
PARN抗体
英文名称：
Anti-PARN Antibody (Clone#OTI4D6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PARN Antibody (Clone#OTI4D6) |
| 指标别名 | DAN;Deadenylating nuclease;Deadenylation nuclease;PARN |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | PARN |
| 克隆号 | OTI4D6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1-266 of human PARN (NP_002573) produced in E.coli. |
| 实际分子量 | 73.3KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Poly(A)-specific ribonuclease (PARN),also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN),is an enzyme that in humans is encoded by the PARN gene.The protein encoded by this gene is a 3'-exoribonuclease,with similarity to the RNase D family of 3'-exonucleases.It prefers poly(A) as the substrate,hence,efficiently degrades poly(A) tails of mRNAs.Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs.This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development,as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. |
| Uniprot ID | O95453 |
| 基因名全称 | poly(A)-specific ribonuclease |
| 蛋白名全称 | Poly(A)-specific ribonuclease PARN |
| 推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索：PARN抗体，PARN单抗，Anti-PARN Antibody (Clone#OTI4D6)